Cowboys VS 49ers Picks, Predictions, and Odds

Dallas Cowboys VS San Francisco 49ers Best Bets - October 8th

Sunday Night Football Picks - Cowboys VS 49ers

Capping off a wild NFL Sunday with a heavyweight clash between two of the top teams in the NFC as the Dallas Cowboys take on the San Francisco 49ers on Sunday Night Football. This primetime tilt will be a rematch from their 2022 postseason matchup in which the 49ers squeaked out the 19-12 victory against their bitter rivals.

With plenty of bad blood shared between both of these squads, why not crank up the intensity level of tonight’s showdown by placing a bet on the Cowboys VS 49ers?

At Canadian Sports Betting, we provide expert insight and analysis on the NFL so you can stuff your bet slip full of winning wagers on tonight’s marquee matchup. Along with our best bets on the Cowboys VS 49ers, we also supply you with helpful betting resources that can elevate your winning potential.

If you’re interested in getting some skin in on the game on tonight’s matchup but aren’t sure where to take your action, be sure to check out our in-depth reviews on the best sports betting sites in Canada.

After carefully vetting each of the top Ontario sportsbooks on the market, we’ve compiled the best NFL betting sites in Canada so you can find a trusted and reliable oddsmaker with ease. Check out our in-depth reviews, sign up using the links provided, and place your first winning wager using our Cowboys VS 49ers picks, predictions, and odds.

Cowboys VS 49ers Odds

TeamMoneyline OddsPoint Spread OddsOver/Under Odds
Dallas Cowboys+150(+3.5) -108(O 45) -112
San Francisco 49ers-180(-3.5) -112(U 45) -108

Odds Courtesy of DraftKings Ontario Sportsbook as of October 8th, 2023

Cowboys VS 49ers Injury Report

Cowboys VS 49ers Best Bets

Moneyline/Point Spread Pick: Dallas Cowboys (ML/+3.5)

Entering into tonight’s Sunday Night Football tilt as underdogs, back the Dallas Cowboys to pull off the upset win on the road as they best the 49ers for the first time since the 2020 season.

While both squads sport sensational defensive fronts, look for the Cowboys to pull ahead in the upcoming matchup thanks to their high-powered passing attack. Rostering multiple speedy receivers that excel at carving through secondary’s, expect the 49ers to have a tough time containing the airmail offence of the Cowboys this evening.

So far this season the 49ers have faced three of the bottom-ten passing offences in the NFL, making tonight’s matchup their first true test against a strong passing team. Expect to see their defence have a tough time in generating stops, forcing them to play from behind for the first time this season, playing into the hands of the Cowboys as they struggle to catchup on the scoreboard

Bank on the underdog Cowboys to hand the 49ers their first loss of the 2023 NFL season, establishing themselves as legitimate Super Bowl contenders, and securing you a hefty payday with this expert pick.

Over/Under Pick: Over 45 Points

In a matchup pitting two of the most versatile offences in the NFL against one another, look for their to be plenty of scoring drives on Sunday Night Football as the Cowboys VS 49ers results in Over 45 points scored.

Coming into Week 5, the 49ers and Cowboys sit at fourth and fifth respectively in points scored per game, both squads averaging 31-points per contest in 2023. With both sides showing no signs of slowing down heading into Sunday Night Football, look for the scoreboard to light up routinely in this primetime collision course.

Expect both teams to utilize trickery as well as unique sets in order to find a winning edge while on offence as they both take on two of the top defensive units in football.

Hammer the Over on the Cowboys VS 49ers and watch as your bankroll rises alongside the box score with this winning point total pick.

Cowboys VS 49ers Player Prop Bets

Dak Prescott Over 1.5 Passing Touchdowns (+120)

Facing a stingy 49ers defence that’s only allowed six total touchdowns through their first four games, look for Cowboys quarterback Dak Prescott to overpower his opposition, passing for Over 1.5 touchdowns this evening.

While he’s only recorded Over 1.5 passing touchdowns once in four games, don’t think that this has had anything to do with Prescott’s play. Sitting in the top-ten of the NFL in QBR, Prescott has been picking apart secondary’s with ease this season.

Look for Prescott and the Cowboys to put an emphasis on their passing attack this Sunday, attacking over the top, and putting up points through the air as the franchise quarterback finishes with Over 1.5 passing touchdowns for a plus-money player prop bet win.

Christian McCaffrey Over 31.5 Receiving Yards (-120)

Looking like an unstoppable force so far this season, look for 49ers running back Christian McCaffrey to continue producing the bulk of his teams offence as he records Over 31.5 receiving yards against the Cowboys.

While the Cowboys have done a solid job of containing tailbacks out of the backfield in passing sets, look for them to have no answer for the world-class skillset of McCaffery.

Having finished with Over 31.5 receiving yards in back-to-back games, look for Run CMC to continue his dual threat dominance as he racks up plenty of yards through the air in order to score you a winning wager on your Cowboys VS 49ers bet slip.

Cowboys VS 49ers Same Game Parlay

One of the best ways to bet on the NFL, same game parlays are as profitable as they are exciting. Allowing bettors to combine game lines and prop bets into single bet slips, you can earn increased odds for each bet selection added to your Cowboys VS 49ers same game parlay.

In order to be paid out as a winner, bettors must be correct on every pick featured in their wager. If any bet selection comes up short, your entire parlay results in a loss.

Score your next big win on the NFL with our juicy Cowboys VS 49ers same game parlay found below and bump up your bankroll with this pre-built bet.

  • CeeDee Lamb Anytime Touchdown Scorer
  • Brock Purdy 225+ Passing Yards
  • Race to 10 Points - Cowboys

Total Odds: (+525)

A great way to gain additional insight ahead of tonight’s primetime clash, the latest Cowboys VS 49ers public betting trends could supply you with valuable information that could elevate your winning potential.

By compiling all of the latest information regarding where the majority of bets are being placed on tonight’s matchup, you can use this information to help generate your next winning wager on Sunday Night Football.

See where the popular money resides ahead of the Cowboys VS 49ers, and formulate your next successful bet with the latest public betting trends.


Dallas Cowboys - 11%

San Francisco 49ers - 89%

Point Spread

Dallas Cowboys (+3.5) - 24%

San Francisco 49ers (-3.5) - 76%


Over 45 Points - 68%

Under 45 Points - 32%

Best Odds & Lines on the Cowboys VS 49ers

Want to score the best bang for your buck on all of your upcoming Sunday Night Football bets? Then be sure to place your next winning wager with the online sportsbook offering the best odds & lines on the Cowboys VS 49ers.

After shopping lines from across the best sports betting sites in Canada, we’ve compiled where you can earn the best possible payout available on the Cowboys VS 49ers.

Find the betting market you’re interested in wagering on below, follow our direct link to the applicable oddsmaker offering the best odds, sign up, and throw down your next bet with maximized winning potential.


Dallas Cowboys - Bet365 (+160)

San Francisco 49ers - Bet365 (-180)

Point Spread

Dallas Cowboys (+3.5) - DraftKings (-108)

San Francisco 49ers (-3.5) - BetMGM (-110)


Over 45 Points - DraftKings (-108)

Under 45 Points - FanDuel (-110)

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Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.