Giants VS Bills Picks, Predictions, and Odds

New York Giants VS Buffalo Bills Best Bets - October 15th

Sunday Night Football Picks - Giants VS Bills

Set to cap off an exciting day of NFL football, we’ve got a battle between New York-based squads as the New York Giants face off against the Buffalo Bills. The Giants enter tonight’s primetime tilt shorthanded as they take on the beast from the AFC East in the surging Bills.

Crank up the intensity level of tonight’s marquee matchup and boost your bankroll with our Giants VS Bills picks, predictions, and odds.

At Canadian Sports Betting, we provide expert insight and analysis on the NFL so you can win big while enjoying the action of Sunday Night Football. Along with our best bets on the Giants VS Bills, we also provide you with helpful betting resources that can elevate your winning potential.

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After thoroughly vetting each of the top Ontario sportsbooks on the market, we’ve compiled the best NFL betting sites in Canada so you can easily find the oddsmaker that’s right for you.

Sign up with the Canadian bookmaker that fits your betting needs today using the links provided on-site and throw down your first winning wager with our Giants VS Bills picks, predictions, and odds.

Giants VS Bills Odds

TeamMoneyline OddsPoint Spread OddsOver/Under Odds
New York Giants+800(+15) -110(O 44) -105
Buffalo Bills-1350(-15) -110(U 44) -115

Odds Courtesy of DraftKings Ontario Sportsbook as of October 15th, 2023

Giants VS Bills Injury Report

Giants VS Bills Best Bets

Moneyline/Point Spread Pick: Buffalo Bills (ML/-15)

Poised to score their fourth win of the 2023 NFL season, expect to see the Bills bully the Giants for four-straight quarters as they cover the whopping two-score spread in tonight’s Sunday Night Football affair.

With the struggling Giants set to be without their starting quarterback Daniel Jones, they are going to have a difficult time producing scoring drives as they face a sensational Bills defence. Averaging the second-fewest points per game in the NFL through five weeks, the Giants are going to have no chance keeping pace with the high-octane Bills offence.

The Bills have had no trouble pummeling teams once they’ve pulled ahead on the scoreboard, having recorded all three of their wins this season by 28-points or more.

Bank on the Bills to cover the spread against the Giants this evening, running up the score in a lopsided beatdown, and wrapping up your NFL Sunday Week 6 with a big win.

Over/Under Pick: Under 44 Points

While the Bills are sure to light up the scoreboard over the course of tonight’s action, bet the Under on total points scored in this Sunday Night Football clash.

With the Giants inability to score, coupled with the Bills successes at pulling out to early leads, expect to see the Bills slow the pace of the game, draining the clock as they secure an easy win. With the Giants unable to stay within striking distance in tonight’s game, look for them to wave the white flag early on, leading to a low final box score.

It may not be the most exciting brand of football on display, but at least it’s profitable, hammer the Under on the Giants VS Bills and watch as your bankroll skyrockets while the scoreboard stays stagnant.

Giants VS Bills Player Prop Bets

Saquon Barkley Over * Receiving Yards (*)

Gabe Davis Anytime Touchdown Scorer (+145)

While Stefon Diggs still remains the alpha in the Bills receiving corps, don’t forget about Gabe Davis as he connects with Josh Allen in the back of the end zone for a juicy win on your Sunday Night Football bet slip.

A speedy wideout that can burn secondary’s in an instant, look for Davis to run deep routes throughout tonight’s primetime contest as he hauls in deep shots down field.

Possessing a nose for the end zone, back Davis to put six-points on the board, scoring on the field as well as on your bet slip with this juicy anytime touchdown scorer wager.

Giants VS Bills Same Game Parlay

One of the best ways to bet on the NFL, same game parlays are as exciting as they are profitable. Providing bettors with the chance combine game lines and prop bets into a single bet slip, your odds will increase for each bet selection added.

In order to win your Giants VS Bills same game parlay, bettors must hit on each pick included, if any fall short, the entire wager results in a loss.

Craft your next bet carefully or take advantage of our Giants VS Bills same game parlay featured below to score your next big win.

  • Tyrod Taylor Over 23.5 Rushing Yards
  • Stefon Diggs Anytime Touchdown Scorer
  • Bills to Score First

Total Odds: (+315)

A great betting resource that can help you formulate your next winning wager, public betting trends provide bettors with information regarding where the popular money resides on tonight’s tilt. By seeing where the majority of bets are being placed this evening, use this information to help influence your upcoming wagers placed on the Giants VS Bills.

Whether you decide to fade the public or ride alongside them, be sure to review the latest Giants VS Bills public betting trends prior to placing your first bet on Sunday Night Football.


New York Giants - 2%

Buffalo Bills - 98%

Point Spread

New York Giants (+15) - 23%

Buffalo Bills (-15) - 77%


Over 44 Points - 76%

Under 44 Points - 24%

Best Odds & Lines on the Giants VS Bills

Score the best bang for your buck on all your bets placed this evening with the best odds & lines available on the Giants VS Bills.

After scouring the market for the most-profitable lines on the market, we’ve compiled where you can score the biggest possible payout on each of the most popular betting markets on the Giants VS Bills.

Find the betting market you wish to wager on, follow our direct links to the applicable sportsbook offering the best lines and odds, sign up, and maximize your winning potential on tonight’s Sunday Night Football action.


New York Giants - FanDuel (+810)

Buffalo Bills - BetMGM (-1100)

Point Spread

New York Giants (+15) - NorthStar Bets (-109)

Buffalo Bills (-15) - FanDuel (-104)


Over 44 Points - DraftKings (-105)

Under 44 Points - FanDuel (-105)

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Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.