NFL Playoffs Divisional Round Best Bets: Cowboys VS 49ers

Get the Latest Odds and Best Bets on the Cowboys VS 49ers

Dallas Cowboys VS San Francisco 49ers Best Bets

The final matchup of the NFL Playoff Divisional round, the Dallas Cowboys and the San Francisco 49ers are set to go head-to-head in a rematch from last years’s postseason showdown. That game came down to the wire and we could be in store for another thrilling contest between these two phenomenal franchises.

It’s officially do or die time for both sides in this high-stakes showdown, which makes this the perfect opportuntity to raise the stakes by placing a bet on the Cowboys VS 49ers. At Canadian Sports Betting, we provide expert betting advice as well as the best moneymaking picks & predictions on the NFL Playoffs.

Not only do we supply you with helpful betting tools and winning wagers on the NFL postseason, but at CSB we also showcase the top online sportsbooks in Canada. If you’re looking to place a bet on the Cowboys VS 49ers, be sure to check out our top ranked NFL betting sites in the country, find the bookmaker that’s right for you, sign up, and place a wager using our best bets on this playoff clash.

Cowboys VS 49ers Picks

Moneyline/Point Spread Pick: San Francisco 49ers (ML/-4)

Set to face off for the first time since their back-and-forth clash in last year’s postseason, look for history to repeat itself tonight as the San Francisco 49ers eliminate the Dallas Cowboys from the NFL Playoffs in back-to-back years.

The 49ers and Cowboys are both strong teams, but the 49ers depth and upside is what will inevitably give them the edge in this contest. The 49ers are arguably the best overall team in football, sporting a high-scoring offence alongside the top-ranked defensive unit in the NFL.

Exceling on both sides of the football, look for the 49ers to control the pace of the matchup, putting the Cowboys into uncomfortable situations, and taking advantage of any and all mistakes made by the Cowboys.

Back the 49ers to clinch their spot in the NFC Championship game for the third time in four seasons after crushing the Super Bowl dreams of the Cowboys. Look for the 49ers to pull ahead and never look back, securing the win and covering the 4-point spread.

Over/Under Pick: Under 46.5 Points

In a showdown between two of the NFL’s most feared defences, look for the score to stay low all game long as both offences struggle to get going against the terrific defensive units on both sides.

Both the Cowboys and 49ers sport fierce defences, with Defensive Player of the Year candidates on each team in Nick Bosa and Micah Parsons, expect there to be difficulties in driving the ball downfield throughout the game. With game changing players ready to make a play at any second, expect the point total to stay low in this high risk high reward tilt.

Bet smart, bet the Under on the Cowboys VS 49ers matchup and earn yourself some dough while the score stays low.

Cowboys VS 49ers Best Player Prop Bets

Don’t just limit yourself to betting on the outcome of the Cowboys VS 49ers, get some skin in the game by pacing a player prop bet on tonight’s NFL Playoff action.

Player prop bets allow you to bet on the performances of the games top players competing in this high-stakes battle. Whether you bet on a player to exceed expectations set by oddsmakers or to fall flat, player prop bets and plenty of excitement to your NFL bet slips.

Dalton Schultz Under 4.5 Receptions

Coming off of an impressive outing against the Tampa Bay Buccaneers in the Wild Card round, bet against tight end Dalton Schultz to repeat his efforts this week against the Niners.

While Schultz has been a consistent producer for the Cowboys this season, look for Dak Prescott to struggle getting the ball to his pass-catching tight end. The 49ers elite linebacker core featuring Fred Warner and Dre Greenlaw will have Schultz under wraps for any pass attempts over the middle of the field, minimizing his chances to haul in receptions.

Bet the Under on Schultz’s total receptions against the 49ers as Prescott looks elsewhere for offensive production this evening.

Brock Purdy Over 1.5 Passing Touchdowns

A sensational young talent in the NFL, Brock Purdy has proven that he belongs in this league and is ready to carve out an impressive career for himself. With Over 1.5 passing touchdowns in his last seven games, back the former Mr. Irrelevant to pick apart the Cowboys secondary and find a target in the end zone at least twice tonight.

Purdy has not only showcased his tremendous arm talent, but playing on an absolutely stacked offence, each pass completed will have a chance to break out for big yardage as well as put six points up on the board. Bet the Over on Purdy’s passing touchdown total as he continue to push the 49ers one step closer to the Super Bowl.

Cowboys VS 49ers Same Game Parlay

One of the hottest NFL betting crazes, same game parlays allows you to wager on multiple aspects of the Cowboys VS 49ers all in one bet. By combining game lines and prop bets into a single wager, the odds will increase with each additional bet added.

In order to win your bet, each selection featured in your parlay must hit in order to be paid out a winner, if even a single pick loses, so does the entire wager.

Create your own customized same game parlay on the Cowboys VS 49ers or take advantage of our pre-built bet that will provide a big-time boost to your bankroll.

  • Tony Pollard Over 49.5 Rushing Yards
  • Dak Prescott 20+ Completions
  • Christian McCaffrey Over 74.5 Rushing Yards

Total Odds: (+500)

A great way to gain insight ahead of the Cowboys VS 49ers playoff tilt, NFL public betting trends provides you with the latest information regarding how others are betting on this highly-anticipated matchup.

By seeing where others are placing their bets, you can better infer how the game may playout based on public perception. Whether you decide to fade the public or ride with them, make sure to use our latest NFL public betting trends when crafting your next winning wager.

Dallas Cowboys - 41%

San Francisco 49ers - 59%

Dallas Cowboys (+4) - 39%

San Francisco 49ers (-4) - 61%

Over 46.5 - 74%

Under 46.5 - 26%

Cowboys VS 49ers Injury Report

Stay up to date with all the latest injury news for the Cowboys VS 49ers matchup using our up-to-date injury report tracker. Below you can see all the players that have had injury designations ahead of tonight’s clash as well as their status entering into the game.

Be sure to factor in the latest Cowboys VS 49ers injury news into your next NFL Playoff bet slip in order to walk away a winner on all your NFL Playof wagers.

Best NFL Lines & Odds

Want to get the most out of your Cowboys VS 49ers bets? Below we have compiled all the best odds & lines from the top online sportsbooks in Canada.

Simply find the betting market you wish to wager on, follow our direct link to the applicable sportsbooks, sign up, and place a bet with maximized winning potential.


Dallas Cowboys - BetRivers (+175)

San Francisco 49ers - DraftKings (-200)

Point Spread

Dallas Cowboys (+4) - FanDuel (-106)

San Francisco 49ers (-4) - BetMGM (-110)


Over 46.5 - Bet365 (-110)

Under 46.5 - FanDuel (-106)

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Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.