NFL Week 5 Sunday Slate Best Bets

Top Picks, Predictions, and Odds on the Afternoon NFL Action in Week 5

NFL Week 5 Best Bets

The NFL is bringing the heat in Week 5 of the 2023 regular season with several highly-anticipated clashes set to take place this Sunday. With no shortage of terrific matchups waiting to be wagered on, why not raise the stakes of the Sunday slate with our Week 5 best bets?

At Canadian Sports Betting, we provide expert NFL betting insight and analysis so you can load up your bet slips with winning wagers this weekend. Below we’ve provided juicy prop bets, point spread picks, and underdog locks so you can find the winning wager that works best for you.

If you’re interested in placing a bet on Week 5 of the NFL season but aren’t sure where take your action, make sure to check out our in-depth reviews of the best sports betting sites in Canada.

After carefully vetting each of the top Ontario sportsbooks on the market, we’ve compiled the best NFL betting sites into one spot so you can find a trusted and reliable oddsmaker with ease.

Sign up using the links provided to the Canadian bookmaker that works best for you and throw down your first winning wager on the NFL Week 5 afternoon slate.

NFL Week 5 Odds

MatchupMoneyline OddsPoint SpreadOver/Under
Jaguars VS Bills+195/-238+5.5/-5.5O/U 48.5
Giants VS Dolphins+525/-750+12.5/-12.5O/U 47.5
Panthers VS Lions+370/-485+9.5/-9.5O/U 44
Ravens VS Steelers-218/+180-4.5/+4.5O/U 38
Texans VS Falcons+110/-130+1.5/-1.5O/U 41.5
Titans VS Colts-130/+110-2.5/+2.5O/U 43.5
Saints VS Patriots-110/-110+1/-1O/U 39
Eagles VS Rams-205/+170-4/+4O/U 50.5
Bengals VS Cardinals-166/+140-3/+3O/U 44.5
Chiefs VS Vikings-185/+154-3.5/+3.5O/U 53
Jets VS Broncos+114/-135+2.5/-2.5O/U 43.5

Odds Courtesy of DraftKings Ontario as of October 8th

NFL Week 5 Expert Picks

Buffalo Bills (-5.5)

Coming off of a statement win after blowing out the Miami Dolphins in Week 4, back the Buffalo Bills to continue their recent string of success as they cover the spread against the Jacksonville Jaguars from Foggy London town.

Facing a Jags squad that has been unimpressive this season, the Bills are sure to turn this into a one-sided affair in a hurry. With the Jaguars lacking the explosive offensive play many had hoped to see from their talented offence, look for them to struggle matching the high-scoring pace of the Bills.

Back the Bills to run up the score, quickly building themselves a lead, and kicking off NFL Sunday Week 5 with a win as they cover the spread and bump up your bankroll.

Philadelphia Eagles (-4)

After escaping with the overtime win against the Washington Commanders last week, look for the Eagles to remain undefeated as they manhandle the Los Angeles Rams on the road, covering the four-point spread.

While the Rams have certainly been a surprise story this season, look for them to have a tough time going toe-to-toe with the reigning NFC Champions. Having been a competitive team on a weekly-basis, sporting emerging star Puka Nacua to now go along a returning Cooper Kupp, the Rams simply don’t have the firepower or depth to compete with the Eagles.

The Eagles have had no trouble running up the score against their opponents this season, utilizing their plethora of offensive weapons to generate yardage, while sporting one of the toughest defensive fronts in the NFL.

Expect to see the Eagles serve the Rams a reality check this Sunday as they cover the spread with ease, keeping their record unblemished, and netting you a sizable payout with this expert ATS pick.

Houston Texans (+110)

Entering into their divisional clash with AFC South rival, the Atlanta Falcons, hammer the underdog Houston Texans as they continue their ascent toward the top of their division standings.

Hot off the heels of a one-sided beatdown delivered to the Pittsburgh Steelers, the Texans looked sensational all-game long in Week 4. With rookie quarterback CJ Stroud emerging as one of the brightest young talents in the league, look for him to have no trouble orchestrating offence against a porous Falcons defence.

The Texans haven’t just been solid offensively, thanks to their strong interior line as well as their blossoming young gamechangers, look for the Texans to take advantage of the turnover prone Falcons, gaining the edge in the matchup quickly and never looking back.

Bet on the underdog Texans to score their third-straight win, besting the Falcons on the road, and earning themselves a winning record for the first time since Week 1 of the 2021 NFL season.

New York Giants VS Miami Dolphins Over 47.5 Points

In a matchup that could turn ugly in a hurry, look for their to be no shortage of points scored in the upcoming New York Giants VS Miami Dolphins tilt.

With the Dolphins averaging a stellar 37.5 points per game, look for them to have a field day as they take on a Giant defence that has allowed an average of 30.5 points against per contest. With the top-scoring offence taking on the leagues worst defence, look for the Fins to quickly light up the scoreboard thanks to their electric offensive skill players.

Bet the Over on the Giants VS Dolphins and watch as your account balance rises alongside the scoreboard in this high-scoring showdown.

Joe Mixon Anytime Touchdown Scorer (-125)

Hoping to put an end to his teams offensive woes in 2023, back Cincinnati Bengals running back Joe Mixon to hit paydirt both for his team, but also for your Week 5 bet slips as an anytime touchdown scorer.

Taking on a rebuilding Arizona Cardinals squad, Mixon is sure to have a heavy workload in their upcoming contest. With the Cardinals having allowed eight of their 11 touchdowns against to running backs so far this season, all indications point towards Mixon having a successful outing in his road trip to Glendale.

Back Mixon to use his versatile skillset to impact the box score of the Bengals VS Cardinals, bet on him as an anytime touchdown scorer and reap the rewards as he punches his way in for six-points.

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Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.