NFL Playoffs Wild Card Best Bets: Seahawks VS 49ers

Get the Latest Odds and Best Bets on the Seahawks VS 49ers

Seattle Seahawks VS San Francisco 49ers Best Bets

It’s officially time for the 2022 NFL Playoffs to begin and we have a terrific matchup set to kickoff this year’s postseason festivities as the Seattle Seahawks take on a division rival in the San Francisco 49ers. It’s do-or-die time in the NFL as there’s no room for error on the path to Super Bowl LVII.

With the stakes of this game at an all-time high, there’s only one way they could be raised and that’s by placing a bet on the Seahawks VS 49ers this Saturday!

At Canadian Sports Betting we provide our readers with the best bets available on the NFL Playoff tilt between the Seahawks VS 49ers, so you can win big leading all the way up to the Super Bowl. Not only can you find amazing moneymaking picks and predictions, but at CSB we also supply you with the top online sportsbooks in Canada.

We’ve carefully vetted and reviewed all the best online betting sites in Canada and compiled our top recommended NFL Betting sites so you can bet without worry on the biggest games of Wild Card weekend. Find the online sportsbook that works best for you, sign up using our direct links, and start placing your bets on the Seahawks VS 49ers today!

Seahawks VS 49ers Picks

The first matchup of this year’s NFL Playoffs is set to be a banger as two teams that know each other well will face off to settle the score and see who will take one step closer to the ultimate prize in football. Both the Seahawks and 49ers have their own unique strengths that could vault them into the win column, but only one squad can move on to the next stage of the postseason tournament.

Entering as the underdog isn’t something the Seahawks are unfamiliar with. Proving naysayers wrong all season long, the Seahawks were one of the top stories of the 2022 NFL season. After moving on from longtime quarterback Russell Wilson, the Seahawks got better, winning two more games than the previous year.

Behind stellar play from Geno Smith as well as the emergence of rookie running back Kenneth Walker III, the new-look Seahawks have certainly turned heads this season and look to do it one more time as they face the powerhouse 49ers.

Just falling short of the top seed in the NFC Playoffs, the 49ers may just be the team to beat in the 2022 NFL Playoffs. Only continuing to get better as the season progressed, Kyle Shanahan’s impressive squad looks primed for another run at Super Bowl glory.

With 2022 “Mr. Irrelevant” Brock Purdy playing exceptionally well as the starting quarterback for the Niners, as well as the phenomenal production of Christian McCaffrey, the 49ers offence has quickly become an intimidating force in the NFL.

Coupling their dangerous offence with the best defensive unit in the league, this could just be the year the 49ers breakthrough and reclaim the Lombardi Trophy for the first time since 1995.

Moneyline/Point Spread Pick: San Francisco 49ers (ML/-9.5)

Poised to cruise through the NFC Wild Card en route to a deep playoff run, the San Francisco 49ers are in a great position to defeat the Seahawks and cover the 9.5-point spread in the process.

The 49ers have looked like a juggernaut in recent weeks, nearly unstoppable on both sides of the football. Stringing together a whopping ten-game win streak to cap off their 2022 regular season campaign, the 49ers beautiful blend of smashmouth football and elite defence is a scary sight for any potential playoff opponent.

In the case of the Seahawks, this is about as unfavourable a tilt as they could have worried for. Already having lost both games played against the 49ers during regular season play, the 49ers seem to be on a different level compared to their opponents.

With Geno Smiths output beginning to dwindle at the worst possible time, along with their defence allowing the third-most rushing yards against per game in the NFL, the Seahawks are at a complete disadvantage in this playoff clash.

Back the 49ers to dismantle the Seahawks, putting together a terrific performance and punching their ticket to the divisional round of the NFL Playoffs.

Over/Under Pick: Under 42.5 Points

While both sides have a track record for running up the score against their opponents, the Under is the way to go in this postseason matchup.

In the two games these two teams played against each other in the regular season, neither game saw the combined score rise above 42.5 points, both tilts finishing with a point total of 34. With no inclinations of this trend changing in the postseason, the Under is where the smart money resides.

With the 49ers positioned well to control the pace of the matchup, look for them to keep the ball on the ground, milking the clock as they plunge through the weak run defence of the Seahawks. With less time on the clock, that means fewer scoring chances, forcing the Seahawks to play against the clock as well as the 49ers.

Bet the Under on the Seahawks VS 49ers and and watch the score stay low while your account balance booms.

Seahawks VS 49ers Player Prop Bets

Not only are there fantastic bets available on the outcome of the Seahawks VS 49ers, you can also wager on several profitable player prop bets to add some flavour to your NFL Playoff bet slip.

Player prop bets allow you to wager on the performances of the game’s top players as they compete to pass the statistical lines set for them by oddsmakers. Whether you bet on a player to exceed the mark set for them or to underperform under the bright lights, there are plenty of spectacular player prop bets to wager on this Wild Card weekend.

Geno Smith Under 1.5 Passing Touchdowns

One of the best comeback stories in recent years, the resurgence of Geno Smith has been a phenomenal story to watch pan out. While the 2022 season will be on to remember in the career of Smith, this game may be one he will want to forget.

In his two games played against the 49ers this season, Smith threw for only a single touchdown when facing the Seahawks divisional rival. With Smith making his NFL Playoff debut on Saturday, look for his output to be diminished as he struggles to produce against the 49ers.

Take the Under on Smith’s passing touchdown numbers as the Seahawks continue searching for answers as to how they can break the code of the 49ers defence.

Christian McCaffrey Anytime Touchdown Scorer

Continuing to keep up his superstar pace on his new team, Christian McCaffrey has been the perfect addition to the 49ers offence.

A versatile player out of the backfield, CMC has taken the 49ers game plan from good to great, fitting like a glove in their gameplan and transforming a team with playoff hopes to Super Bowl contenders. Set to eat up yards against the Seahawks, look for McCaffrey to hit paydirt in his first playoff matchup since 2017.

McCaffrey was a premier scoring threat during the regular season piling up 10 total touchdowns in 11 games played under the 49ers banner. Back CMC to find the end zone at anytime over the course of this game to secure you a winning ticket on your NFL Playoff player prop bets.

Seahawks VS 49ers Same Game Parlay

One of the most exciting ways to bet on the NFL, same game parlays allow bettors to combine game lines and prop bets to create their own customized bets with fantastic odds attached.

Just like a multi-game parlay, same game parlays increase in odds with each additional bet selection added providing you with phenomenal odds depending on how many/what kinds of bets you add to your parlay. While the payouts can be glorious remember if even a single bet selection included loses, so does your entire bet.

Craft your own Seahawks VS 49ers same game parlay or make use of our pre-built bet found below.

  • DK Metcalf Under 59.5 Receiving Yards
  • George Kittle Over 29.5 Receiving Yards
  • Brock Purdy Under 219.5 Brock Purdy

Total Odds: (+550)

A terrific way to gain additional insight into a matchup, NFL public betting trends allows you to see how others are betting on a specific matchup before the game takes place.

By seeing where the public money lays you can better infer based on the publics perception how a game may play out. Whether you decide to fade the public or ride with them, this information can be a useful betting tool for any bettor that’s torn on where they want to lean heading into a game.

Seattle Seahawks - 15%

San Francisco 49ers - 85%

Seattle Seahawks (+9.5) - 32%

San Francisco 49ers (-9.5) - 68%

Over 42.5 - 63%

Under 42.5 - 37%

Seahawks VS 49ers Injury Report

Critical to the success of your NFL Playoff bets, reviewing the latest NFL injury report for both teams in a matchup could make the difference between winning and losing your next wager.

By seeing the latest updates for both team injured players you can better understand how a contest may play out if one of the games top players is unable to suit up. It only takes the absence of one player to shift the outcome of the game and therefore the outcome of your bets. Be sure to review the latest Seahawks VS 49ers injury report below before placing a bet on this upcoming tilt.

Best NFL Lines & Odds

It’s the Playoffs, a time to go big or go home, and at Canadian Sports Betting, we want you to take that same mantra into your bets this postseason. Stop wasting your time placing wagers with online betting sites that provide mediocre odds and start wagering with our top online sportsbooks providing the best lines & odds on the Seahawks VS 49ers.

Below you will find all the sportsbooks offering the most profitable lines & odds on the Seahawks VS 49ers so you can maximize your winning potential on this postseason showdown. Simply find the betting market you’re interested in wagering on, follow our helpful direct link to the applicable bookmaker, sign up, and place a bet with the best possible payout available on the Seahawks VS 49ers.


Seattle Seahawks - Bet365 (+425)

San Francisco 49ers - BetRivers (-435)

Point Spread

Seattle Seahawks (+9.5) - DraftKings (-110)

San Francisco 49ers (-9.5) - BetRivers (-108)


Over 42.5 - FanDuel (-108)

Under 42.5 - BetMGM (-110)

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Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.