Sunday Night Football Best Bets: Week 3

All the Best Bets for the Duel Between the San Fransisco 49ers and the Denver Broncos

SNF Best Bets: 49ers VS Broncos

On Sunday night a major matchup between two Super Bowl hopefuls will transpire as the San Fransisco 49ers (1-1) take on the Denver Broncos (1-1). Both teams have been faced with adversity early on into the 2022 season as both teams will be playing desperate to avoid falling to under .500.

With this highly anticipated primetime tilt set to kickoff, there’s never been a better time to get in on the action and place a wager on the 49ers VS Broncos on Sunday Night Football. Below you’ll find all of the best bets for this marquee matchup that are sure to net you your next big win.

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Standard Bets

Regardless if you’re new to NFL betting or have an expansive history of NFL betting, you can never go wrong wagering on the traditional bet markets like moneylines, point spreads, and point totals. All of these betting options are easy to wager on and can help you develop more in-depth betting strategies.

Below you can find our picks for the 49ers VS Broncos matchup!

Moneyline/Point Spread Pick: San Fransisco 49ers ML/(-1.5)

Facing adversity on the road, we got our money on the San Fransisco 49ers to both win and cover the 1.5-point spread. With Jimmy Garoppolo firmly behind the helm of the 49ers’ offence once again, they have looked revitalized on the field.

After losing Trey Lance to a severe ankle injury Jimmy G picked up where he left off and didn’t miss a beat, helping secure the win over the Seahawks in Week 2. Along with Jimmy G’s, the eminent return of All-Pro tight end George Kittle to the 49ers offence only makes this team even more dangerous.

Facing a Broncos team that has been completely underwhelming so far this year, look for the 49ers to control this game’s temp, maintain possession, and put pressure on the Broncos’ offence to produce. The Broncos offence has looked out of sorts through two weeks of play, don’t back them until we can see some offensive consistency and discipline from their sideline.

Over/Under Pick: Under 44.5 Total Points

In a matchup between two teams that love to run the football, the score is going to be fairly low. With the point total set at a modest 44.5 points, there’s plenty of room for teasing with this line, but the under is a great look regardless.

With the 49ers being a grind-it-out, run-heavy team, look for them to make this matchup ugly and enforce their game plan on the Broncos. The Broncos are no strangers to this, however as they love to move the ball on the ground and fight in the trenches for additional yardage.

Both of these squads have a terrific run defence as well, both coming into Week 3 in the Top 5 in total rushing yards against.

A large concern hovers over the heads of the Broncos coaching staff as well in this matchup as their play-calling and clock management has been downright horrendous so far this season. If they continue their communication and decision-making issues into this one, Kyle Shannahan and his 49ers will exploit this and keep the game low-scoring and play chess while the Broncos are stuck playing checkers.

Best Player Prop Bets

Other than wagering on the game’s outcome, player prop bets are a fun way to wager on any game. Here you can bet on player-specific events occurring within a matchup.

Below you can find some of our best player prop bets that are sure to add some juice to your 49ers VS Broncos betslip.

Deebo Samuel Over 31.5 Rushing Yards

The dual-threat player for the 49ers, Deebo Samuel is always a prime candidate to register a big play whether it’s through the air or on the ground. Entering this matchup Samuel has averaged 52.5 rushing yards per game, with his over/under set at 31.5 this is an absolute steal for bettors.

As we all know the 49ers are going to keep their offence rolling through the run, expect Samuel to get several touches and maybe even pop off for a big-time play downfield. Bet the over on Samuel’s rushing yards.

Russell Wilson Under 231.5 Passing Yards

Russell Wilson has never been afraid to let the pigskin fly, but in this matchup, we could see him take a backseat to the running back duo of Javonte Williams and Melvin Gordon and result in a low passing yard total.

With a banged-up wide receiver corps, Wilson won’t have the best options when looking to move the ball deep and will have a difficult time getting it to his check-down with the 49ers sporting one of the best front-sevens in the NFL.

Don’t back Russ, bet the under on his passing yard total.

CSBs Best Same Game Parlay

Same game parlays (SGP) are one of the hottest ways to bet on any sporting event, allowing for players to stack multiple wagers on a single event into one betslip.

At CSB we want to give you a same game parlay that could hand you your first SGP victory. We kept it simple but this safe SGP has some great value attached for all bettors to take advantage of.

  • 49ers (-1.5)
  • Deebo Samuel Under 64.5 Receiving Yards
  • Russell Wilson 1+ Passing Touchdowns

Total Odds: (+340)

Knowing where the public is leaning can be a fantastic tool when determining how you want to wager on a matchup. Whether you decide to fade or ride with the public betting trends, having an idea of how the masses are betting is a great way to analyze how you see a matchup.

Find the public betting trends for the 49ers VS Broncos below.


  • San Fransisco 49ers - 58%
  • Denver Broncos - 42%

Point Spread

  • San Fransisco 49ers - 74%
  • Denver Broncos - 26%


  • Over 44.5 - 27%
  • Under 44.5 - 73%

Injury Reports

Being informed on who is going to be suiting up for any matchup is essential before placing any wager. If a star player is a game-time decision, it may be best to steer clear of wagering on their team. Find all of the reported player injuries heading into the 49ers VS Broncos matchup below.

San Fransisco 49ersDenver Broncos
OL Colton Mckivitz (Questionable, Undisclosed)WR Tyrie Cleveland (Questionable, Hamstring)
DL Arik Armstead (Questionable, Foot)WR KJ Hamler (Questionable, Knee/Hip)
OL Daniel Brunskill (Questionable, Undisclosed)DL Mike Purcell (Questionable, Undisclosed)
TE Tyler Kroft (Out, Knee)DL Dre’Mont Jones (Questionable, Undisclosed)
RB Tyrion Davis-Price (Out, Ankle)LB Jonathon Cooper (Questionable,
DL Kalia David (Out, Undisclosed)WR Jerry Jeudy (Questionable, Ribs/Shoulder)
CB Jason Verrett (Out, Undisclosed)CB Pat Surtain II (Questionable, Shoulder)
QB Trey Lance (IR, Ankle)LB Josey Jewell (Questionable, Calf)
DL Jordan Willis (IR, Undisclosed)CB Darius Phillips (Questionable, Undisclosed)
RB Elijah Mitchell (IR, Knee)DT D.J. Jones (Questionable, Undisclosed)
CB Jimmie Ward (IR, Hamstring)OL Billy Turner (Questionable, Undisclosed)
LB Curtis Robinson (IR, Ankle)OL Quinn Meinerz (Doubtful, Undisclosed)
TE Jordan Matthews (IR, Knee)OL Tom Compton (Out, Back)
DL Maurice Hurst (IR, Biceps)S Justin Simmons (IR, Quadriceps)
CB Michael Ojemudia (IR, Elbow)
TE Greg Dulcich (IR, Undisclosed)
OL Casey Tucker (IR, Toe)
WR Tim Patrick (IR, Knee)
LB Christopher Allen (IR, Foot)
RB Damarea Crockett (IR, Knee)

Best Lines & Odds

The process of comparing odds between sportsbooks and breaking down where you’ll get the best value for your bet can be a painstaking ordeal. That’s why at Canadian Sports Betting, we’ve scoured through the best lines from top sportsbooks so you know where and what to bet on this primetime matchup.


Point Spread


Want more NFL Betting news and analysis? Be sure to check back frequently on Canadian Sports Betting for all the best NFL betting tips and news including weekly picks and NFL Futures Odds.

Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.