NFL

Thursday Night Football Best Bets Week 13

Get the Latest Odds and Best Bets for the Buffalo Bills VS New England Patriots


Thursday Night Football Week 13 Picks

It’s a showdown between divisional rivals on primetime as the Buffalo Bills take on the New England Patriots on Thursday Night Football. This is a matchup that could completely shift the NFL Playoff bracket as both teams currently are jockeying alongside the Miami Dolphins for control of the top spot in the AFC East.

Want to raise the stakes of this highly-anticipated rivalry game? Place a bet on the Bills VS Patriots and win big on one of the NFLs most heated rivalries. There’s no shortage of amazing bets to be placed on this primetime matchup so go ahead, get in the game, and place a bet on the Bills VS Patriots.

Want to get some skin in on the game but aren’t sure where to throw down your bets? At Canadian Sports Betting, we don’t just provide the best bets and expert analysis on all the biggest NFL games, we also supply you with the best online sportsbooks on the market.

Read our comprehensive sportsbook reviews, find the top NFL betting site that’s right for you, and place a bet using our betting picks & predictions to score your first winning wager on the NFL.

Signup & Download DraftKings Today

Buffalo Bills VS New England Patriots Best Bets

In their first meeting since the AFC Wild Card a season ago, the Buffalo Bills will travel to Foxborough to face the New England Patriots. These bitter divisional rivals will show no love lost between them in what is set to be an intense and fiery matchup on Thursday Night Football.

Playing their second week in a row on Thursday, the Bills will look to extend their winning streak to three games against the Patriots. Last week the Bills feasted on American Thanksgiving against the Detroit Lions, squeaking out the narrow victory off a late game-winning field goal courtesy of Tyler Bass.

Facing a team that has historically dominated the Bills, they will have to bring their A-game to take down Bill Belichicks squad.

Looking at this years Patriots team, while on paper they don’t jump out at you but once again they find themselves deep in the AFC Playoff hunt. Coming off a shootout loss to the Minnesota Vikings in their last outing, the Pats have proven they can keep up with the top teams of the NFL on both sides of the field.

Over the past four seasons, the Patriots have won five of the last eight matchups against the Bills. Looking to capture their biggest win of the season, the Patriots will look to continue their success against the Bills on Thursday Night Football.

Moneyline/Point Spread Pick: Buffalo Bills (ML/-3.5)

They may not have the best track record when going head-to-head with the Patriots, but look for the Bills to further solidify themselves as the top dog of their division. In a clash of styles, this matchup is sure to have a lengthy feeling out process, but once the Bills get the ball rolling the Patriots will have no chance at keeping up.

The Bills are simply too good, with a high-octane offence and one of the best defensive units in the NFL, the Patriots would need to play a near perfect game to escape Gillette Stadium with the win. The Pats defence has been what’s kept them competitive in the post-Brady era, but so far no team has successfully solved the riddle on how to stop the dynamic play of Josh Allen and the Bills.

On top of this, while the Mac Jones led offensive unit for the Patriots has looked solid over the past few weeks, look for this success to come to a screeching halt against the Bills. The Pats have struggled against the leagues top ranked defences and this trend is sure to continue on Thursday Night Football.

Back the Bills to squash the Patriots, securing their spot at the top of the AFC East standings, landing you a solid payday as they win the game and cover the spread on Thursday Night Football.

Over/Under Pick: Over 43.5 Points

Even with both teams sporting two of the best defensive units in the NFL, look for the Over to hit in this primetime matchup.

Both the Bills and Patriots offences have been clicking this season, resulting in multiple high-scoring affairs. With high scoring averages on the season making the Over and attractive bet already, but the historically this has been a high-scoring rivalry.

Aside from a few cold weather bashes between these two teams, the final combined score has resulted in Over 43.5 points in three of their last four meetings, four out of the last five if you include their playoff matchup from last season.

With the trend looking to continue on primetime, bet the Over on Thursday Night Football as both the Bills and Patriots pull out all the stops to get a winning edge over their opponent.

Thursday Night Football Player Prop Bets

Looking for some extra action to get in on for the Bills VS Patriots? We’ve got you covered with some of the best player prop bets available for this primetime matchup.

There’s plenty of talent set to take the field in this game, providing bettors with several fantastic player prop bets to be made on Thursday Night Football. Find our top picks for the Bills VS Patriots and score a win using our best NFL player prop bets.

Stefon Diggs Anytime Touchdown Scorer

Arguably the best wideout in all of football, Stefon Diggs is once again carving out a fantastic season for himself. With 1110 receiving yards racked up to go along with nine receiving touchdowns, the All-Pro wide receiver has looked unstoppable this season.

Even with ample coverage and increased attention placed on limiting his production, Diggs is always a threat to find the end zone. Back Josh Allen’s favourite weapon to hit paydirt, providing you with a hefty payout as he gets his team on the board and he continues his tremendous 2022 season.

Mac Jones Over 230.5 Passing Yards

Mac Jones has had a shaky start to his NFL career. With several ups and downs and sporadic play, Jones has looked like he’s finally cleaned up his act on the field and has been playing exceptionally in recent weeks.

In his last two games Jones has been passing efficiently, completing nearly 80% of his passes and keeping the ball out of the hands of his opposition, Picking up big yardage totals over the past two weeks, back Jones to continue slinging the rock with the best of them, looking to outduel Josh Allen and passing for Over 230.5 yards against the Bills.

Bills VS Patriots Same Game Parlay

Looking for a way to get the most out of your Bills VS Patriots bets? Placing a same game parlay is easy, fun, and most importantly, profitable.

While they can be difficult to win, same game parlays allow for you to build unique bet slips with amazing odds attached so you can win big on a small wager amount. The catch is with every added bet selection your odds increase, but if even a single wager included loses, the entire bet goes out the window.

Place a same game parlay on the Bills VS Patriots on Thursday Night Football, or use our pre-built parlay to help you get your feet wet and you wallet filled with same game parlays.

  • Rhamondre Stevenson Anytime Touchdown Scorer
  • Hunter Henry Over 19.5 Receiving Yards
  • Devin Singletary Over 49.5 Rushing Yards

Total Odds: (+425)

A fantastic way to gain additional insight on any NFL matchup, public betting trends allows you to see where other bettors are placing their money on a specific game.

By reviewing the latest public betting trends you can better see how others are leaning in a particular matchup and you can use this to help decide where you want to throw down your next bet. Check out the latest Bills VS Patriots public betting trends and take the opinion of others into account before you place a bet on Thursday Night Football.

Buffalo Bills - 84%

New England Patriots - 16%

Buffalo Bills (-3.5) - 78%

New England Patriots (+3.5) - 22%

Over 43.5 - 71%

Under 43.5 - 29%

Bills VS Patriots Injury Report

Before placing a bet on tonight’s primetime matchup, don’t jump the gun and place a wager until you’ve done your research. One of the most important areas to review before betting on the NFL is reviewing the latest injury reports.

If even a single top player is out for the game, this could drastically change the final outcome of the game, and therefore effect your bets. Check out the latest Bills VS Patriots injury report and take this into consideration before placing a bet on Thursday Night Football.

Best NFL Thursday Night Football Lines & Odds

If you’re going to place a bet, make sure it’s with the sportsbook that is offering the best odds & lines available. While line shopping can be a long and tiring process, we’ve sped it up for you.

Below you can find the best odds & lines on the Bills VS Patriots, as well as the sportsbook that provides them. Find the betting market you’re interested in wagering on, use our direct links to find the sportsbook providing the top odds, and place a bet that will maximize your winning potential.

Buffalo Bills - DraftKings (-175)

New England Patriots - BetRivers (+165)

Buffalo Bills (-3.5) - PointsBet (-107)

New England Patriots (+3.5) - PointsBet (-107)

Over 43.5 - PointsBet (-107)

Under 43.5 - PointsBet (-107)

Want to stay up to date with all of the latest NFL betting news? Canadian Sports Betting has all of the best bets, picks, & predictions on all the top sports.

Our sports betting news is updated daily so you can place winning wagers weekly or on NFL Futures like odds on the upcoming Super Bowl.

Follow us on Twitter @cdnbetting for more betting updates, news, and exclusive picks!


Matt Eichhorn

Matt Eichhorn

Having worked in the Sports Gambling industry since 2020, Eichhorn has expertise in all things sports betting. With experience covering various major North American sports leagues he has a wide array of knowledge to draw from when crafting his work.